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. 2014 Dec 9;9(12):e114429. doi: 10.1371/journal.pone.0114429

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© 2014 Sugimoto et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Plasma membrane fractions were extracted from HAECs. Changes in the activity of MT1-MMP are shown after HMGB-1 stimulation. Results are expressed as mean±S.D. of 3 separate experiments performed in pentaplicate. ^* P<0.05 vs. 0 minute before HMGB-1 stimulation.