Table 3.
Mean Scores (and Standard Deviations) for Primary and Secondary Efficacy Measures by Minority Status
| Measure | Assessment Visit
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline M (SD, n) |
Week 2 M (SD, n) |
Week 4 M (SD, n) |
Week 6 M (SD, n) |
Week 8 M (SD, n) |
Week 12 M (SD, n) |
Week 16 M (SD, n) |
Week 20 M (SD, n) |
Week 24 M (SD, n) |
|
| HAM-A Total | |||||||||
| European Americans | 25.7 (2.5,17) | 19.9 (4.5,17) | 17.4 (4.6,17) | 13.7 (5.3,17) | 13.4 (6.4,17) | 10.5 (5.5,16) | 8.1 (5.0, 12) | 7.3 (6.2, 12) | 7.5 (6.0, 11) |
| African Americans | 26.8 (2.2,8) | 23.1 (5.9,8) | 17.3 (8.0,8) | 14.0 (8.9,8) | 12.5 (9.7,8) | 12.4 (9.8,8) | 9.1 (9.5,7) | 4.2 (3.2,6) | 4.7 (3.5,6) |
| HAD Anxiety | |||||||||
| European Americans | 13.1 (2.9,17) | 10.4 (4.3,17) | 10.1 (3.7,17) | 8.9 (4.1,17) | 8.1 (3.5,16) | 6.6 (3.2,16) | 6.7 (4.4,12) | 6.3 (4.5,12) | 6.4 (2.3,10) |
| African Americans | 14.4 (4.5,8) | 14.6 (5.0,8) | 12.8 (5.9,8) | 10.8 (5.6,8) | 11.6 (5.9,8) | 8.0 (6.0,8) | 8.0 (6.6,7) | 5.8 (5.1,6) | 5.8(5.1,5) |
| HAD Depression | |||||||||
| European Americans | 10.4 (6.0,17) | 8.1 (5.7,17) | 7.4 (4.7,17) | 6.4 (4.8,17) | 6.6 (4.9,16) | 5.7 (4.2,16) | 5.8 (4.0,12) | 5.2 (4.5,12) | 5.9 (3.7,10) |
| African Americans | 7.8 (4.8,8) | 9.0 (4.2,8) | 8.0 (5.8,8) | 6.5 (5.8,8) | 8.0 (6.5,8) | 5.5 (5.8,8) | 5.6 (6.6,7) | 2.7 (3.4,6) | 2.2 (3.3,5) |
| HAM-D-17 Total | |||||||||
| European Americans | 13.1 (2.3,17) | 7.2 (3.5,16) | 6.1 (4.0,11) | ||||||
| African Americans | 12.9 (2.0,8) | 6.7 (4.5,6) | 3.2 (3.6,6) | ||||||
| CGI-Severity | |||||||||
| European Americans | 4.7 (0.6,17) | 3.9 (0.6,17) | 3.6 (0.6,16) | 3.1 (0.9,17) | 3.1 (1.1,17) | 2.4 (0.8,16) | 2.1 (1.0,12) | 1.8 (1.1,11) | 1.9 (1.0,11) |
| African Americans | 4.9 (0.4,8) | 4.4 (0.7,8) | 3.5 (1.2,8) | 2.9 (1.4,8) | 2.8 (1.6,8) | 2.6 (1.6,8) | 2.2 (1.5,6) | 1.3 (0.5,6) | 1.7 (1.2,6) |
| CGI-Improvement | |||||||||
| European Americans | 2.4 (2.0,17) | 3.2 (0.7,17) | 2.6 (0.7,16) | 2.5 (0.7,17) | 2.4 (1.2,17) | 1.7 (0.8,16) | 1.5 (0.7,12) | 1.5 (0.8,11) | 1.4 (0.7,11) |
| African Americans | 3.5 (1.4,8) | 3.4 (0.7,8) | 2.8, (1.2,8) | 2.3 (1.3,8) | 2.3 (1.3,8) | 2.1 (1.2,8) | 1.8 (1.2,6) | 1.2 (0.4,6) | 1.3 (0.5,6) |
| GHQ/12QL | |||||||||
| European Americans | 33.9 (7.8,17) | 25.8 (7.0,16) | 24.5 (6.9,10) | ||||||
| African Americans | 35.3 (5.5,8) | 23.8 (8.1,8) | 22.5 (6.7,6) | ||||||
| PSWQ | |||||||||
| European Americans | 61.1 (10.1,17) | 49.1 (10.9,16) | 47.4 (9.8,11) | ||||||
| African Americans | 62.0 (8.5,8) | 48.8 (14.5,8) | 44.7 (14.0,6) | ||||||
| SF-12 – Physical Component | |||||||||
| European Americans | 47.7 (12.7,16) | 49.5 (11.5,16) | 47.2 (13.3,11) | ||||||
| African Americans | 41.5 (15.2,8) | 38.6 (12.9,7) | 42.3 (12.0,6) | ||||||
| SF-12 – Mental Component | |||||||||
| European Americans | 30.6 (10.4,16) | 41.7 (9.3,16) | 41.9 (11.5,11) | ||||||
| African Americans | 26.5 (6.6,8) | 40.8 (14.0,7) | 46.8 (12.2,6) | ||||||
Note. HAM-A = Hamilton Anxiety Rating Scale. HAD Anxiety = Hospital Anxiety Depression Anxiety Scale. HAD Depression = Hospital Anxiety Depression – Depression Scale. HAM-D-17 = 17 item Hamilton Rating Scale for Depression total score. CGI = Clinical Global Impression. PSWQ = Penn State Worry Questionnaire. GHQ/12QL = General Health Questionnaire Quality of Life scale.