Table 2.
Results of the final Cox regression model and risk scores of independent factors based on 1223 patients with all parameters available (training data set, score population)
| Independent factor | HR* (95% CI†) | P | Risk score | |
|---|---|---|---|---|
| Category according hierarchical model17 | Del(17p) | 6.0 (4.2 – 8.6) | <.001 | 6 |
| s-TK | >10.0 U/L | 2.1 (1.5-2.9) | <.001 | 2 |
| s-β2m | >3.5 mg/L | 2.3 (1.4-3.6) | .001 | 2 |
| s-β2m | >1.7 and ≤3.5 mg/L | 1.7 (1.1-2.7) | .01 | 1 |
| IGHV MS | Unmutated | 1.9 (1.5-2.5) | <.001 | 1 |
| ECOG PS | >0 | 1.7 (1.3-2.1) | <.001 | 1 |
| Category according hierarchical model17 | Del(11q) | 1.4 (1.03-2.0) | .03 | 1 |
| Sex | Male | 1.3 (1.01-1.6) | .026 | 1 |
| Age | >60 y | 1.3 (1.04-1.7) | .045 | 1 |
*
Hazard ratio.
†
Confidence interval.