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. 2014 Mar 10;123(22):3398–3405. doi: 10.1182/blood-2013-11-537555

Table 4.

Response rate in relapsed/refractory MCL patients receiving idelalisib

Category All patients (N = 40) Receiving <150 mg bid* (n = 24) Receiving ≥150 mg qd (n = 16)
ORR 16 (40) 5 (21) 11 (69)
CR 2 (5) 0 2 (12.5)
PR 14 (35) 5 (21) 9 (56.3)
SD 19 (47.5) 15 (62.5) 4 (25)
PD 4 (10) 4 (16.7) 0
NE 1 (2.5) 0 1/16 (6.3)

Data are presented as number (%) of patients.

bid, twice daily; CR, complete response; NE, not evaluable; PR, partial response; qd, daily.

*

Dose cohorts include 150 mg daily, 150 mg twice daily × 21 days, 50 mg twice daily, and 100 mg twice daily.

Dose cohorts include 300 mg daily, 150 mg twice daily, 200 mg twice daily, and 350 mg twice daily.