Table 2. Characteristics of additional algorithmically defined anaphylaxis cases, by specific cause.
Characteristic | Fatal allergic reactions and anaphylaxis deaths identified by algorithmN=593 | |||
---|---|---|---|---|
Drug and serum N=306 (51.6%) | Venom N=48 (8.1%) | Food N=24 (4.0%) | Unspecified N=215 (36.3%) | |
Males, n (%) | 139 (45.4) | 38 (79.2) | 13 (54.2) | 83 (38.6) |
Age, median (IQR§) | ||||
Females | 65 (49.0-79.0) | 51 (39-64) | 64 (25-75) | 64.5 (51-79) |
Males | 61.0 (44-75) | 54.5 (45-65) | 41 (34-63) | 63 (50-76) |
Race, n (%) | ||||
Non-Hispanic White | 190 (62.1) | 38 (79.2) | 14 (58.3) | 171 (79.5) |
African-American | 93 (30.4) | 7 (14.6) | 3 (12.5) | 31 (14.4) |
Hispanic | 16 (5.2) | 2 (4.2) | 1 (4.2) | 10 (4.7) |
Place of death | ||||
Inpatient | 210 (68.6) | 11(22.9) | 8 (33.3) | 95 (44.2) |
Outpatient (including ER*) | 59 (19.3) | 22 (45.8) | 10 (41.7) | 59 (27.4) |
Community (including deadon arrival) | 37 (12.1) | 15 (31.3) | 6 (25.0) | 60 (27.9) |
Associations with asthma, angioedema, and hypotension | ||||
Asthma | 119 (38.9) | 8 (16.7) | 10 (41.7) | 142 (66.1) |
Angioedema | 99 (32.4) | 10 (20.8) | 12 (50.0) | 45 (20.9) |
Hypotension | 47 (15.4) | 19 (39.6) | 1 (4.2) | 25 (11.6) |
IQR – interquartile range
ER – emergency room