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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Biol Psychiatry. 2014 Jun 12;77(1):59–65. doi: 10.1016/j.biopsych.2014.05.024

Figure 2.

Figure 2

Trajectories of Comorbidities Characterizing Three Distinct Sub-clusters of ASD Defined by Electronic Health Record Data. Shown in red are the top three co-morbidities from cluster 1 where seizures rise to a prevalence of 80%. Shown in blue are the top three co-morbidities from cluster 2 with an early childhood peak of infections. Not shown (because lower ranked) is a rise in inflammatory bowel disease that continues to rise through adolescence. Shown in green are the top three co-morbidities in cluster 3 which are characterized by anxiety and hyperkinetic activity. Not shown (because lower ranked) is a rise in schizophrenia that accelerates with onset of adolescence.