Skip to main content
. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Biol Psychiatry. 2014 Jun 12;77(1):59–65. doi: 10.1016/j.biopsych.2014.05.024

Table 1.

Overlap between sets of genes found to be implicated in autism and those in immunological regulation and long-term potentiation.

Two sets intersected Genes in the intersection
Gene Ontology Immune Genes
(http://bit.ly/KIcYOZ) and the Simons
Foundation autism gene database
(https://gene.sfari.org)		 ADA CD44 HLA-A C4B ITGA4
NOS2A PTGS2
IL1RAPL1 APC ITGB3 ITGB7
ADORA2A ALOX5AP HRAS ADRB2
NRP2 RPS6KA2 LAMB1 (~10% of SFARI
genes)
Gene Ontology Immune Genes
(http://bit.ly/KIcYOZ) and KEGG Long
Term Potentiation (hsa:04720)		 RAF1 PRKCA CREBBP MAP2K2 BRAF
MAP2K1 RPS6KA2 MAPK3 MAPK1 HRAS
EP300 CAMK2A CAMK2G PRKACA ATF4
(~21% of KEGG LTP genes)
KEGG T cell receptor signaling (hsa:04660)
and KEGG Long Term Potentiation
(hsa:04720)		 RAF1 PPP3R2 PPP3CC PPP3R1 MAP2K2
MAP2K1 NRAS CHP2 MAPK3 MAPK1
HRAS KRAS PPP3CB PPP3CA CHP (~21%
of KEGG LTP genes)