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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Sep 28;1846(2):485–493. doi: 10.1016/j.bbcan.2014.09.006

Figure 1. The members of semaphorin family.

Figure 1

This classification is based on the similarity in domain architecture and the species in which it is expressed. All the members of this family share the characteristic Sema domain, which is known to have a seven blade beta propeller topology (represented here as a heptagon). Semaphorins can also be classified based on their property of being trans-membrane, membrane anchored or secreted. Abbreviations, CRD: Cystine rich domain, GPI: Glycophosphotidyl inositol.