Table 2.
Validation-testing sample characteristics
| Phenotypes | Total Number | Female (%) | Mean Age3 | Years Followup4 (StDev) | ICD-9 Diagnosis Count (StDev) | |||
|---|---|---|---|---|---|---|---|---|
| POS1 | NEG2 | POS1 | NEG2 | POS1 | NEG2 | |||
| Acute Myocardial Infarction | 363 | 158 | 199 (38.2%) | 73.8 | 37.9 (9.7) | 33.5 (12.2) | 1848 (1475) | 1384 (1304) |
| Acute Liver Injury | 44 | 6 | 23(46%) | 69.3 | 34.9 (10.6) | 35.2 (10.0) | 1880 (1568) | 2550 (951) |
| Atrial Fibrillation | 36 | 35 | 31 (44%) | 79.8 | 29.2 (13.1) | 31.7 (14.5) | 1345 (811) | 1468 (1100) |
| Cataracts | 244 | 110 | 210 (59.32%) | 75.2 | 39.7 (9.8) | 37.9 (11.2) | 1395 (1004) | 864 (616) |
| CHF | 60 | 36 | 51 (52%) | 70 | 35.4 (10.0) | 26.1 (13.8) | 1614 (1184) | 623 (647) |
| Dementia | 303 | 70 | 203 (54.4%) | 84 | 36.9 (11.3) | 37.4 (8.64) | 1579 (980) | 1438 (1067) |
| Type 2 Diabetes | 113 | 52 | 99 (60%) | 67 | 36.3 (12.3) | 34.0 (13.6) | 1447 (781) | 925 (781) |
| Diabetic Retinopathy | 40 | 46 | 39 (45.4%) | 71.6 | 35.1 (12.7) | 37.9 (13.8) | 2032 (1158) | 1614 (1158) |
| Deep Vein Thrombosis | 217 | 870 | 614 (56%) | 76 | 38.3 (9.9) | 38.9 (10.2) | 1947 (1604) | 1269 (836) |
1
POS indicates Positive examples
2
NEG indicates Negative examples
3
Mean age calculated by (Year of data pull (2012) - Birth Year)
4
Years Follow-up calculated by determining difference between first and last diagnosis date
Note: Phenotype models were validated using these validation cohorts.