Figure 8. WMN but not CAP inhibits stimulus evoked neurotransmitter release in TRPV1−/− NMP.
A. Mean amplitudes (nA) in response to 1 Hz stimulus evoked end plate currents (EPC) of control, CAP (1 µM) or WMN (20 µM) treated NMP (n = 4–6 muscles and 14–20 neuromuscular junction, from 6 mice) at the end of 120 min. after the application of either vehicle alone (first bar) or CAP or WMN (second and third bars respectively). ** represents statistical significance for P<0.001.