Figure 2.

Effects of CORM-2 on survival in an E coli-induced murine model of sepsis. Mice were divided into four groups as follows: control (saline), E coli, E coli+CORM-2, E coli+iCORM-2. Mice were infected by E coli followed by immediate intravenous administration of CORM-2 or iCORM-2. All E coli infected mice and E coli infected mice with iCORM-2 treatment died within 36 h, while CORM-2 administration significantly increased the survival rate which reached 55%. n=8.