TABLE I.
Demographics of Children with Sickle Cell Anemia Screened in the Silent Infarct Transfusion Trial
| Variable | History of grade retention (N = 94) |
No history of grade retention (N = 442) |
P-value |
|---|---|---|---|
| Age of child at registration in years | 10.4 | 9.2 | <0.001 |
| Gender (male, %) | (67.0) | (49.1) | 0.002a |
| Silent infarct (%) | (28.7) | (32.6) | 0.466a |
| Hematocrit level | 22.2 | 23.2 | 0.007 |
| Pain event rate (episodes per 3 years) | 0.59 | 0.55 | 0.260b |
| Last grade that the child completed in school (median) | 3 | 2 | 0.095b |
| IEP in place (%) | (47.9) | (12.0) | <0.001a |
| 504 Plan in place (%) | (7.4) | (9.8) | 0.486a |
| Medicaid health care coverage for child (%) | (82.8) | (64.5) | 0.001a |
| Marital status of parents: unmarried (%) | (68.1) | (58.6) | 0.088a |
| Age of mother in years | 34.6 | 34.6 | 0.962 |
| Age of father in years | 38.4 | 37.2 | 0.225 |
| Number of people in household | 4.9 | 4.5 | 0.052 |
| Yearly household per capita income in U.S. dollars | 5668 | 9365 | <0.001 |
| Yearly household per capita income in U.S. dollars (median) | (IQR 5 5833) | (IQR 5 8929) | <0.001b |
| Head of household education (overall test) | 0.010a | ||
| Less than high school graduation (%) | 24.5 | 14.3 | |
| High school diploma or GED (%) | 36.2 | 31.0 | |
| Any amount of college (%) | 39.4 | 54.8 |
IEP, individualized education program; GED, general education development.
a
Chi-square test.
b
Mann–Whitney U test.