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. Author manuscript; available in PMC: 2015 Sep 28.
Published in final edited form as: J Control Release. 2014 Jun 12;190:240–253. doi: 10.1016/j.jconrel.2014.05.057

Fig. 5.

Fig. 5

Controlled release of immunoreactive TT from self-healed PLGA Al(OH)3/PLGA microspheres. The release kinetics of TT is shown for the initial burst (A) and long-term release (B) into PBST + 0.2% BSA at 37 °C Formulations were unencapsulated Al(OH)3 (●), TT/PLGA microspheres prepared by w/o/w emulsion solvent evaporation (▲), and TT/adjuvant/plasticizer/PLGA microspheres prepared by self-healing encapsulation 3.2 wt.% Al(OH)3-PLGA-3.5 wt.% trehalose-5 wt.% diethyl phthalate (DEP) (□), 3.2 wt.% Al(OH)3-PLGA-3 wt.% trehalose-5 wt.% tributyl acetylcitrate (TBAC) (◆), and 3.2 wt.% Al(OH)3-PLGA-1.5 wt.%trehalose-1.5% MgCO3-5 wt.% TBAC (○).

Reproduced from [97] with permission.