Table 5.

Langmuir model fitted parameters ^a and estimated fraction of acids occupied at maximal peptide absorption after 1 day at 37 °C. Data from [45].

Peptide	Polymer	K (μM−1)	Γ0 (μmol/g PLGA)	Γmax (μmol/g PLGA)	Total acids (μmol/g PLGA)	Fraction acids occupied b
Leuprolide	RG 502H	0.77	1.5	229	185	1.24
Octreotide	RG 502H	1.6	8.5	163	185	0.88
Octreotide	RG 503H	1.2	2.9	81	94	0.86

^aSorption values determined by fitting to 1 day absorption data using $\Gamma ={\Gamma }_0+\frac{{\Gamma }_{1}K{C}_f}{1+K{C}_f}$ where Γ_max = Γ₁ + Γ₀.

^bFraction acids occupied estimated from ratio of Γ_max to total acids determined in polymer.