Table 2.

Summary of stabilizing effect of excipients on the three peptides

Formulation#	Peptide	CMCS added	Salt added	% native peptide
				3 day	7 day	14 day	21 day	28 day
1	Oct	−	−	−	92.7± 0.5	88.1 ± 0.3	80.8 ± 0.4	76.3 ± 0.4
2	Oct	+	−	−	94.0 ± 0.6	90.2 ± 0.4	86 ± 2	77 ± 2
3	Oct	−	CaCl2	−	97.7 ± 0.2	94.5 ± 0.2	91.0 ± 0.7	85.2 ± 0.9
4	Oct	−	MnCl2	−	97.7 ± 0.1	95.4 ± 0.5	91.1 ± 0.6	85.9 ± 0.5
5	Oct	+	CaCl2	−	97.4 ± 0.4	95.9 ± 0.4	92.8 ± 0.1	89.2 ± 0.4
6	Oct	+	MnCl2	−	98.1 ± 0.2	96.7 ± 0.6	94.0 ± 0.7	90.1 ± 0.4
7	sCT	−	−	93.5 ± 0.9	91 ± 3	84 ± 3	83 ± 7	−
8	sCT	+	−	100.0 ± 0.1	92 ± 3	88 ± 6	83.8 ± 0.8	−
9	sCT	−	CaCl2	99.9 ± 0.2	94.3 ± 0.3	85 ± 2	87 ± 6	−
10	sCT	−	MnCl2	97 ± 1	94 ± 3	86 ± 2	88 ± 4	−
11	sCT	+	CaCl2	100.0 ± 0.1	100.0 ± 0.1	99.7 ± 0.5	98 ± 2	−
12	sCT	+	MnCl2	99.3 ± 0.9	99 ± 2	99 ± 2	98.3 ± 0.3	−
13	hPTH	−	−	77 ± 2	68 ± 2	56 ± 3	46.1 ± 0.8	−
14	hPTH	+	−	83 ± 2	71.7 ± 0.5	58.2 ± 0.7	50 ± 3	−
15	hPTH	−	CaCl2	90 ± 3	88 ± 3	76 ± 2	62 ± 4	−
16	hPTH	−	MnCl2	95.2 ± 0.6	92 ± 2	89 ± 3	84 ± 2	−
17	hPTH	+	CaCl2	93.7 ± 0.8	88.3 ± 0.8	73 ± 2	69 ± 3	−
18	hPTH	+	MnCl2	94.9±0.7	90.5 ± 0.5	72 ± 2	61 ± 4	−