Fig 4.
HBx promotes the growth of HCC xenograft tumors induced by RMP. (A). Nude mice were inoculated subcutaneously with SMMC-7721 cells stably transfected with RMP expression vectors for tumor formation. Two weeks after inoculation, tumors in the nude mice were injected every other day with indicated vectors, or PBS as a control. Tumor size was measured everyday after inoculation and expressed as the mean volume of tumors from five mice, which was depicted graphically. (B). Tumors were dissected at 24th day after inoculation and photographs of tumors from each group are shown. Quantitation of mean tumor weight is shown in (C). Student's t test, *, p<0.05, relative to controls.