Table 1. Binding free energy of the hnRNPC CLZ domain according to tetramer combinations of mouse and human hnRNPC1 and C2. The total binding free energy for different combinations of human (hu) and mouse (mu) hnRNPC1 and C2 CLZ domains, estimated from MMPBSA calculations.

CLZ tetramer	(ΔGMM/PBSA)/(kcal⋅mol−1)
HuC13–HuC21	−112.07
HuC13–MuC21	−103.25
MuC13–HuC21	−107.22
MuC13–MuC21	−94.59