Table 1.

Adverse skin reactions according to the National Cancer Institute (NCI) criteria [7]

	Skin Lesions
Grade 1	Macular or papular eruption or erythema without associated symptoms
Grade 2	Pruritic macular or papular eruption or erythema with covering less than 50% of body surface area
Grade 3	Symptomatic, generalized erythroderma or macular, papular or vesicular eruption, or desquamation covering more than 50% of body surface area
Grade 4	Generalized exfoliative dermatitis or ulcerative dermatitis