Table 2.
The effects of the LPS and antioxidant treatments on the local production levels of bax, caspase 3, and bcl-2 in pulmonary epithelial cells
| Treated group | Local production level of bax (%) mean±SD | Local production level of caspase 3 (%) mean±SD | Local production level of bcl-2 (%) mean±SD |
|---|---|---|---|
| IP saline | 10.0±3.5 | 10.8±5.3 | 21.1±3.3 |
| IP LPS | 77.5±5.5a | 80.0±8.0a | 8.8±3.5c |
| IP LPS + Erdosteine (150 mg/kg) | 48.8±7.9b | 51.3±6.9b | 43.8±12.2d |
| IP LPS + NAC (150 mg/kg) | 2.8±2.6b | 43.9±3.3b | 45.6±5.3d |
Statistical analysis:
a
Significantly increased compared to the negative control group (p<0.0001).
b
Significantly reduced compared to the positive control group (p<0.0001).
c
Significantly reduced compared to the negative control group (p<0.0001).
d
Significantly increased compared to the positive control group (p<0.0001).