Table 2.
Susceptibility data for dermatophytes species against five antifungal agents using the E-test method
| Species (n) | Antifungal agent | MIC range* | MIC50 | MIC90 |
|---|---|---|---|---|
| T. rubrum (43) | Amphotericin B | 0.012–8 | 0.50 | 1.5 |
| Fluconazole | 0.19–48 | - | - | |
| Itraconazole | 0.038–1.5 | 0.50 | 0.19 | |
| Caspofungine | 0.02–3 | 1 | 0.064 | |
| Ketoconazole | 0.032–8 | - | - | |
| T. mentagrophytes (7) | Amphotericin B | 0.19–8 | 0.70 | 4 |
| Fluconazole | 2–256 | - | - | |
| Itraconazole | 0.094–1.5 | 0.25 | 1.5 | |
| Caspofungine | 0.032–4 | 0.25 | 2 | |
| Ketoconazole | 0.064–8 | 2 | 8 | |
| M. canis (5) | Amphotericin B | 0.50–3 | 0.50 | 1 |
| Fluconazole | 2–8 | - | - | |
| Itraconazole | 1–32 | - | - | |
| Caspofungine | 0.125–0.50 | 0.50 | 0.125 | |
| Ketoconazole | 32 | - | - | |
| T. tonsurans (5) | Amphotericin B | 0.125–6 | 0.50 | 0.50 |
| Fluconazole | 256 | - | - | |
| Itraconazole | 0.016–0.50 | 0.125 | 0.125 | |
| Caspofungine | 0.032–2 | 0.032 | 0.032 | |
| Ketoconazole | 32 | - | - | |
| E. floccosum (4) | Amphotericin B | 32 | - | - |
| Fluconazole | 256 | - | - | |
| Itraconazole | 0.25–0.50 | 0.25 | 0.50 | |
| Caspofungine | 0.25–0.50 | 0.25 | - | |
| Ketoconazole | 32 | - | - | |
| T. violaceum (2) | Amphotericin B | 0.75 | - | - |
| Fluconazole | 8–24 | - | - | |
| Itraconazole | 0.125–0.50 | - | - | |
| Caspofungine | 0.125–0.50 | - | - | |
| Ketoconazole | 32 | - | - |
MIC: Minimal inhibitory concentration
*
MIC (μg/mL−1)