Table 3.
Variable | Univariate analyses | Multivariate analyses | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Time on waiting list (per year) | 1.27 | 1.00-1.62 | 0.05* | 1.62 | 1.07–1.78 | 0.02* |
Creatinine (per 10 μmol/l) | 1.03 | 1.01–1.06 | 0.01* | 1.07 | 1.03–1.11 | <0.001* |
LVH | 3.78 | 1.12–12.72 | 0.03* | 6.23 | 1.18–22.31 | 0.004* |
Male | 0.43 | 0.19–0.98 | 0.04* | 0.23 | 0.11–0.65 | 0.02* |
LAV/BSA above 32.1 ml/m2 | 3.11 | 1.27–7.57 | 0.01* | 6.60 | 1.70–18.58 | 0.02* |
Delayed graft function | 2.42 | 1.08–5.64 | 0.03 | 3.12 | 1.02–9.57 | 0.05* |
Cerebrovascular disease | 6.76 | 2.58–17.78 | 0.05* | 3.12 | 0.91–23.7 | 0.07 |
Peripheral vascular disease | 3.36 | 1.00–11.37 | 0.05* | 7.38 | 0.51–52.3 | 0.21 |
Age at transplantation (per year) | 1.04 | 1.00–1.08 | 0.05* | 1.02 | 0.96–1.26 | 0.43 |
BMI (per kg/m2) | 1.02 | 0.94–1.12 | 0.69 | |||
Biopsy-proven acute rejection | 2.76 | 0.37–5.68 | 0.21 | |||
LVSD | 2.38 | 0.88–6.47 | 0.08 | |||
Ischemic heart disease | 1.33 | 0.45–3.91 | 0.61 | |||
LV dilation | 1.16 | 0.34–3.90 | 0.82 | |||
Diabetes mellitus | 0.59 | 0.25–1.31 | 0.19 | |||
Heart failure | 0.86 | 0.12–6.40 | 0.88 | |||
Current/Ex smoker (ref never) | 1.58 | 0.67–3.72 | 0.30 | |||
Systolic BP (per mmHg) | 1.02 | 0.99–1.04 | 0.15 | |||
Diastolic BP (per mmHg) | 0.98 | 0.94–1.02 | 0.26 | |||
Dyslipidemia | 1.67 | 0.71–3.99 | 0.24 | |||
RRT time to CMR (years) | 0.92 | 0.81–1.05 | 0.21 | |||
Previous RRT type | ||||||
PD | 1.00 | |||||
HD | 1.29 | 0.17–9.79 | 0.80 | |||
Hemoglobin (per g/dl) | 0.65 | 0.97–1.13 | 0.13 | |||
Albumin (per g/l) | 0.83 | 0.65–1.05 | 0.13 | |||
Phosphate (per mmol/l) | 0.43 | 0.07–2.75 | 0.37 | |||
Calcium (per mmol/l) | 5.45 | 0.11–12.54 | 0.40 | |||
ACEI/ARB therapy pre-transplant | 0.52 | 0.16–1.76 | 0.29 | |||
ACEI/ARB therapy post-transplant | 0.42 | 0.10–1.80 | 0.24 |
Hazard ratios (95% confidence intervals (CI)) are shown. Variables highlighted with (*) were added to the multivariate Cox model. Abbreviations: LV left ventricle, LVH left ventricular hypertrophy, LVSD left ventricular systolic dysfunction, BMI body mass index, BP blood pressure, RRT renal replacement therapy, PD peritoneal dialysis, HD hemodialysis. *p < 0.05