Table 2.

Features of cases in the second season, divided in four groups

	Clinical suspicion	Clinical suspicion	Non-suspicion	Non-suspicion
	RT-PCR positive	RT-PCR negative	RT-PCR positive	RT -PCR negative
	N = 7	N = 42	N = 7	N = 250
	(Figure 1, group C)	(Figure 1, group D)	(Figure 1, group E)	(Figure 1, group F)
Male, n	4	30	1	147
Age, months, mean (range)	14,8 (1,2-49,6)	4,8 (0,1-21,7)	3,8 (0,6 - 8,7)	7,6 (0,1-89,4)
Clinical features
In-hospital cases, n	6 (85,7%)	30 (71,4%)	5 (71,4%)	182 (72,8%)
Fever, n	3 (42,9%)	18 (42,9%)	1 (14,2%)	131 (52,4%)
Coughing, n	7 (100%)	41 (97,6%)	7 (100%)	207 (82,8%)
Rhinorrhea, n	7 (100%)	39 (92,9%)	7 (100%)	231 (92,4%)
Paroxysmal cough, n	6 (85,7%)	25 (59,5)	1 (14,2%)	27 (10,8%)
CRP > 40 mg/L, n	0 (0%)	3 (7,1%)	1 (14,2%)	26 (10,4%)
Oxygen therapy necessary, n	2 (28,6%)	15 (35,7%)	2 (28,6%)	105 (42,0 %)
Nasogastric feeding, n	1 (14,3%)	5 (11,9%)	0 (0,0%)	27 (10,8%)
Wheezing, n	3 (42,9%)	15 (35,7%)	1 (14,2%)	113 (45,2%)
Apnoe, n	0 (0%)	3 (7,1%)	0 (0,0%)	10 (4,0%)
Days of illness, mean (range)	18,3 (5–37)	9,7 (2–42)	10,4 (5–18)	8,3 (1–35)
Disease severity score, mean (range)	9,9 (0–19)	11,7 (0–24)	9,6 (3–18)	13,4 (0–27)
Disease severity score
<6	2	9	2	65
7-13	3	16	3	55
14-19	2	14	2	75
>20	0	3	0	55
Clinical diagnosis
Exclusively URTI	0	23	4	133
Exclusively LRTI	0	0	0	1
Combined URTI/LRTI	7	18	3	106
No URTI or LRTI	0	1	0	10
Pertussis diagnosis
PCR throat swab material, n	4	x	0	x
PCR NWS, n	3	x	7	x
Serology, positive, n	1	x	0	x
Culture, positive n	0	x	0	x
Viral (co)infection
None	1	7	2	37
1 virus	6	21	3	146
≥ 2 virusses	0	14	2	67
Antibiotic therapy
None	0	26	4	158
Amoxicillin, n	1	9	2	94
Claritromycine, n	7	7	1	8