Table 3.
Burden of herpes zoster and herpes zoster-related pain at baseline in each age-group
| Age group (years) | 70-74 (N = 220) | 75-79 (N = 163) | 80-84 (N = 137) | ≥85 (N = 89) | p-value |
|---|---|---|---|---|---|
| ZBPI score: mean (SD) | |||||
| Interference score* | 3.2 (2.3) | 3.1 (2.4) | 3.5 (2.3) | 3.6 (2.7) | 0.582 |
| SF-12† | |||||
| PCS score: mean (SD) | 42.7 (8.9) | 41.8 (9.4) | 37.9 (10.0) | 34.2 (8.9) | <0.001 |
| Physical functioning | 57.9 (35.3) | 53.8 (34.9) | 40.7 (34.2) | 26.6 (33.6) | <0.001 |
| Vitality | 36.6 (25.7) | 33.5 (23.0) | 28.8 (23.5) | 25.4 (23.0) | 0.004 |
| MCS score: mean (SD) | 41.1 (10.2) | 38.7 (11.5) | 39.6 (10.9) | 41.0 (9.8) | 0.413 |
| HADS: mean (SD) ‡ | |||||
| Depression score | 6.3 (4.0) | 7.9 (4.4) | 8.1 (5.2) | 9.8 (4.9) | 0.001 |
| Anxiety score | 6.9 (4.2) | 7.9 (4.1) | 7.3 (4.6) | 7.1 (4.3) | 0.237 |
HADS = Hospital Anxiety and Depression Scale; MCS = Mental component summary; PCS = Physical component summary; SD = Standard deviation; SF-12 = 12-item Short-Form health survey; ZBPI = Zoster Brief Pain Inventory.
*From 0, no interference to 10, maximal interference.
†Scores < 50 indicates health-related quality of life (HRQoL)impairment.
‡Scores > 8 indicate probable anxiety or depression.