Table 2. Toxicity (N=58 evaluable patients).
| Toxicity | Grade 3 toxicity | Grade 4 toxicity |
|---|---|---|
|
| ||
| Hematologic | ||
| Neutropenia | 12 (21%) | 4 (7%) |
| Thrombocytopenia | 9 (16%) | 0 (0%) |
| Anemia | 2 (3%) | 0 (0%) |
|
| ||
| Fatigue | 16 (28%) | 4 (7%) |
|
| ||
| Allergic reaction | 15 (26%) | 0 (0%) |
|
| ||
| Myalgia/arthralgias | 10 (17%) | 0 (0%) |
|
| ||
| Depression/anxiety | 5 (9%) | 3 (5%) |
|
| ||
| Nausea/vomiting | 5 (9%) | 0 (0%) |
|
| ||
| Neurotoxicity | 3 (5%) | 0 (0%) |
|
| ||
| Headache | 2 (3%) | 0 (0%) |
|
| ||
| Elevated liver function tests | 2 (3%) | 0 (0%) |
|
| ||
| Elevated creatinine | 0 (0%) | 0 (0%) |
|
| ||
| Alopecia | 0 (0%) | 0 (0%) |
|
| ||
| Fever | 0 (0%) | 0 (0%) |