Skip to main content
. 2014 Dec 10;5:214. doi: 10.3389/fendo.2014.00214

Table 1.

Factor expression in distraction and compression forces in rabbit DO model.

Factor Outcome Reference
BMP-4 (mRNA) Acceleration of expression of BMP-4 when compression applied Kim et al. (65)a
TGF-β1 (mRNA) Increased and sustained expression of TGF-β1 when compression applied Kim et al. (65)a
Osteonectin (mRNA) Sustained expression of osteonectin up to 3 weeks post-compression in the accordion group Kim et al. (65)a
VEGF (protein) Increased expression of VEGF in the compression group Mori et al. (66)b

DO, distraction osteogenesis; BMP, bone morphogenic protein; VEGF, vascular endothelial growth factor; TGF-β1, transforming growth factor beta.

aControl group (distraction of 1 mm/day for 8 days) and experimental group (distraction of 1 mm/day for 10 days followed by a 3-day latency period after which they compressed 1 mm/day for 2 days) – rabbit mandibular DO.

bControl group (distraction of 0.7 mm/day for 14 days) and experimental group (distraction of 0.7 mm/day for 14 days then compression of 0.7 mm/day for 3 days) – rabbit tibial DO.