Table 1.
Target molecules and active components of rikkunshito.
| Target molecules | Active components (Crude drug) | Structure | Reference |
|---|---|---|---|
| 5-HT2b/2cR | 3,3,4,5,6,7,8- Heptamethoxyfkvone (Aurantii nobilis pericarpium) |  |
Takeda et al. (2008) |
| Hesperetin an aglycon form of hesperidin (Aurantii nobilis pericarpium) |  |
Takeda et al. (2008) | |
| Isoliquiritigenin (Glycyrrhizae radix) |  |
Takeda et al. (2008) | |
| GHS-R | Atractylodin (Atractylodis lanceae rhizoma) |  |
Fujitsuka et al. (2011) |
| Ghrelin deacylating enzymes | 10-Gingerol (Zingiberis rhizoma) |  |
Sadakane et al. (2011) |