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. 2014 Nov 28;46(11):e123. doi: 10.1038/emm.2014.73

Figure 4.

Figure 4

miR-27 inhibits mitochondrial fission. CHANG liver cells expressing mitochondria-targeted YFP (mtYFP) were transiently transfected with pre-miR-27, anti-miR-27 or control miRNA. Forty-eight hours after transfection, the mtYFP (a) or Mitotracker (b) signals were observed under a fluorescence microscope. The data are representative of three independent experiments. (c) Scoring of mitochondrial morphology for the indicated cells. Forty-eight hours after transfection, each cell was placed into one of three morphological categories, and the percentages of cells with the indicated mitochondrial morphologies (intermediate, elongated or fragmented forms) from 100 cells were calculated from three independent experiments. The data represent the mean±s.e.m. from three independent experiments. **P<0.01.