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. 2014 Oct 17;15(12):4621–4626. doi: 10.1021/bm501467h

Figure 3.

Figure 3

Ratio of FA to oligonucleotide length determines the extent of aggregation. (a) Light scattering from solutions of 3′-cA20 strands as a function of FA anchor length. (b) Light scattering from solutions of 3′-cA-C24 anchored oligonucleotides as a function of the number of DNA bases. The red box indicates the same strand, 3′-cA20-C24. (c) Membrane incorporation compared to DAG for combinations of 3′-cA-C24 with increasing numbers of DNA bases. (d) Incorporation vs time for DAG and 5′-Anch100-C24/3′-cA50-C24-DNA. Error bars are standard deviation of at least three independent measurements.