Table 2.
Comparison of biochemical and haematological measurements before and after antiretroviral treatment
| Laboratory measurements | Pre-ART Mean (SD) | 15thDay Post-ART Mean (SD) | Mean Difference (Pre-ART minus Post-ART) | 95% CI of mean difference | p-value from paired t-test |
|---|---|---|---|---|---|
| ALAT (U/L) | 17.87 (20.48) | 19.25 (12.01) | −1.37 (23.10) | −5.73-2.99 | 0.53 |
| ASAT (U/L) | 17.32 (11.87) | 21.02 (14.12) | −3.70 (16.61) | −6.84- -0.56 | 0.02 |
| Haemoglobin (g/dl) | 10.86 (2.63) | 10.36 (1.92) | 0.50 (2.29) | 0.08-0.92 | 0.02 |
| Mean cell volume (fl) | 79.62 (7.93) | 83.49 (9.13) | −3.86 (8.98) | −5.95- -1.78 | 0.0004 |
| Absolute leucocyte count (10 3 /μl) | 6.21 (3.44) | 4.84 (1.76) | 1.37 (3.62) | 0.66-2.09 | 0.0002 |
| Absolute platelet count (10 5 /μl) | 2.72 (1.07) | 2.69 (1.14) | 0.03 (1.18) | −0.20- 0.25 | 0.82 |
ART = antiretroviral therapy, ALAT = alanine aminotransferase, ASAT = aspartate aminotransferase, CI = confidence interval.