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. Author manuscript; available in PMC: 2014 Dec 10.
Published in final edited form as: J Hepatol. 2014 Apr 5;61(2):210–218. doi: 10.1016/j.jhep.2014.04.001

Table 3.

Estimated unadjusted incidence rates and relative hazards of hip fracture (with 95% confidence intervals) for treated chronic hepatitis B (CHB)-infected patients compared to uninfected persons, overall and by race/ethnicity, among the U.S. Medicaid populations of California, Florida, New York, Ohio, and Pennsylvania.

Treated CHB Infection CHB-Uninfected Propensity-Score
Matched and
Adjusted
Hazard Ratio
of Hip Fracture,
Treated CHB vs.
Uninfected
(95% CI)
No.
Patients
(% Total)
No. (%)
Hip
Fractures
Person-
Years
Raw Hip Fracture
Incidence Rate,
Events/1,000
person-years
(95% CI)
No.
Patients
(% Total)
No. (%)
Hip
Fractures
Person-
Years
Raw Hip Fracture
Incidence Rate,
Events/1,000
person-years
(95% CI)

Total* 7,777
(100%)
27
(0.3%)
16,598 1.6
(1.1 – 2.4)
979,751
(100%)
13,668
(1.4%)
3,448,002 4.0
(3.9 – 4.1)
1.17 (0.76 – 1.78)

Asian/PI 5,724
(73.6%)
16
(0.3%)
12,142 1.3
(0.8 – 2.1)
232,957
(23.8%)
2,088
(0.9%)
866,499 2.4
(2.3 – 2.5)
0.98 (0.59 – 1.64)

White 759
(9.8%)
7
(0.9%)
1,675 4.2
(1.7 – 8.6)
317,008
(32.4%)
8,550
(2.7%)
1,123,939 7.6
(7.4 – 7.8)
2.19 (0.94 – 5.09)

Black 384
(4.9%)
2
(0.5%)
869 2.3
(0.3 – 8.3)
124,182
(12.7%)
1,019
(0.8%)
489,963 2.1
(2.0 – 2.2)
3.39 (0.61 – 18.80)

Hispanic 569
(7.3%)
0
(0.0%)
1,123 0.0
(0.0 – 2.7)
270,527
(27.6%)
1,142
(0.4%)
852,265 1.3
(1.3 – 1.4)

Abbreviations: CHB, chronic hepatitis B; CI, confidence interval; PI, Pacific Islander

*

Persons of unknown race are included in all totals except for hazard ratios. Persons of unknown race are not displayed separately.

Hazard ratios of hip fracture in CHB-infected versus uninfected persons are based on propensity score-matched Cox regression analyses with further adjustment for age, sex, race, and interactions for age*race and age*sex. Persons of unknown race are not included in hazard ratios.

Relative hazards of hip fracture were not determined because no fracture events occurred in this group.