Figure 5. An excitable network model accounts for confinement-induced polarity.

(A) Kymograph of model variable showing the formation of patches that represent randomly emerging pseudopods. (B) Kymograph of model variable in the presence of channel boundaries (gray). All model parameters are chosen identically in (A) and (B). Inset: Zoom of structures forming between 400 and 700 sec. Examples of slanted structures are indicated by dashed black lines to guide the eye. (C,D) Spatial profiles of at the time points indicated by red wedges in (A) and (B), respectively. (E) Schematic diagram of the excitable network model (green) with polarity module (blue).