Table 6.
Nitroxoline | Controls | p-value | |||
---|---|---|---|---|---|
Demographic parameter | n | Median (range) | n | Median (range) | |
Age (years) | 234 | 48 (18–89) | 232 | 47 (18–85) | 0.520 |
-up to 45 years | 234 | 113 (48.3%) | 232 | 115 (49.6%) | 0.745 |
Height (cm) | 234 | 165 (150–185) | 231 | 165 (145–187) | 0.290 |
Weight (kg) | 234 | 62 (43–100) | 232 | 64 (42–102) | 0.125 |
Body mass index (kg /m2) | 234 | 23.0 (15.9–41.3) | 231 | 23.2 (15.6–38.0) | 0.038 |
Heart rate (min −1) | 231 | 80 (52–172) | 231 | 80 (56–120) | 0.354 |
Systolic BP (mmHg) | 232 | 120 (80–195) | 231 | 130 (100–190) | 0.025 |
Diastolic BP (mmHg) | 232 | 80 (60–120) | 231 | 80 (50–120) | 0.410 |
No hypertension (SBP ≤ 140 mmHG) | 232 | 165 (71.1%) | 231 | 137 (59.3%) | 0.004 |
Mild hypertension (SBP > 140 mmHG) | 232 | 46 (19.8%) | 231 | 63 (27.3%) | |
Moderate hypertension (SBP > 160 mmHG) | 232 | 17 (7.3%) | 231 | 22 (9.5%) | |
Severe hypertension (SBP > 180 mmHG) | 232 | 4 (1.7%) | 231 | 9 (3.9%) | |
Diabetes mellitus | 234 | 11 (4.7%) | 232 | 6 (2.6%) | 0.230 |
Duration of urinary symptoms (d) | 165 | 3 (1–30) | 168 | 3 (1–21) | 0.442 |
Pretreatment with antimicrobials* | 234 | 16 (6.8%) | 232 | 8 (3.4%) | 0.060 |
Only unspecific pretreatment# | 234 | 25 (10.7%) | 232 | 28 (12.1%) | 0.667 |
*antibiotics, chemotherapeutics.
#spasmolytics, analgetics, tea etc.