Table 8.
Evaluation set | Nitroxoline | Controls | Difference (%) (95%-CI) | Odds ratio (95%-CI) |
---|---|---|---|---|
mMITT | 192/211 (91.0%) | 203/213 (95.3%) | −3.4 (−9.7 to 3.0) | 0.47 (0.21 to 1.06) |
PP | 184/200 (92.0%) | 197/206 (95.6%) | −2.2 (−8.2 to 3.7) | 0.47 (0.19 to 1.14) |
mPP | 185/205 (90.2%) | 197/210 (93.8%) | −2.9 (−9.9 to 4.1) | 0.60 (0.28 to 1.27) |
mMITT-modified microbiological intention to treat; PP-per protocol; mPP-modified per protocol.
Difference: nitroxoline – controls.
Odds Ratio: nitroxoline vs controls.
Estimation by logistic regression with random center effect.