Table 2.
Comparison of CMR Parameters between Patients With and Without the Endpoint
| All Patients (n=215) | Transplant Free Survival (n=191) | Death or Transplant (n=24) | P Value | |
|---|---|---|---|---|
| Heart rate at CMR | 79 [66, 91] | 77 [65, 91] | 83 [66, 96] | 0.25 |
| EDVi (mL/BSA1.3) | 94 [76, 115] | 93 [75, 113] | 131 [90, 166] | 0.001 |
| EDVi (mL/BSA) | 107 [87, 130] | 104 [86, 127] | 128 [106, 182] | 0.001 |
| ESVi (mL/BSA1.3) | 42 [32, 57] | 41 [31, 54] | 55 [36, 94] | 0.007 |
| ESVi (mL/BSA) | 48 [36, 64] | 46 [36, 62] | 64 [39, 104] | 0.01 |
| SVi (mL/BSA1.3) | 50 [42, 60] | 50 [42, 57] | 63 [47, 81] | 0.008 |
| SVi (mL/BSA) | 57 [48, 67] | 56 [48, 65] | 65 [57, 85] | 0.007 |
| Ejection fraction (%) | 55 [47, 61] | 55 [48, 60] | 53 [38, 63] | 0.26 |
| Ejection fraction < 40% | 24 (11%) | 16 (8%) | 8 (33%) | 0.002 |
| Massi (g/BSA1.3) | 55 [43, 68] | 52 [43, 65] | 75 [56, 103] | 0.001 |
| Massi (g/BSA) | 60 [48, 81] | 58 [48, 77] | 84 [60, 104] | 0.002 |
| Mass/volume ratio (g/mL) | 0.57 [0.48, 0.70] | 0.57 [0.48, 0.70] | 0.55 [0.46, 0.73] | 0.62 |
| ≥ Moderate AVVR | 25 (12%) | 21 (11%) | 4 (17%) | 0.50 |
| ≥ Moderate SLVR | 10 (5%) | 8 (4%) | 2 (8%) | 0.31 |
| Positive LGE* | 43 (33%) | 35 (30%) | 8 (47%) | 0.18 |
Values are expressed as median [25th, 75th percentile] or n (%).
*
Subgroup analysis with 132 patients.
Abbreviations: AVVR = atrioventricular valve regurgitation; BSA = body surface area; EDV = end-diastolic volume; ESV = end-systolic volume; LGE = late gadolinium enhancement; SLVR = semilunar valve regurgitation; SV = stroke volume.