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. 2014 Oct 27;592(Pt 23):5235–5250. doi: 10.1113/jphysiol.2014.279968

Figure 7. IL-6R neutralization and antalarmin alter colonic mucosal protein expression.

Figure 7

Bar charts illustrating the ratios of expression of occludin (A, n = 5), claudin 2 (B, n = 5) and Cav3.2 (C, n = 5) over the β actin loading control, phosphoSTAT3 as a fraction of total STAT3 (D, n = 5), SOCS3 as a fraction of the β actin loading control (E, n = 5) and phosphoERK1/2 over total ERK1/2 (F, n = 5) in mucosal samples from the distal colon of SD and WKY rats treated with saline, anti-IL-6 receptor antibody (xIL-6R) and xIL-6R with antalarmin (ant). Asterisks indicate *P < 0.05, **P < 0.01 and ***P < 0.001.