Table 2. Estimated genetic variance explained by eQTL SNPs and non-eQTL SNPs.
h2 | Ref | eQTLs (n = 25,658) | Non-eQTL SNPs (n = 1.7 million) | |||||
Vg | Vp | Vg/Vp | Vg | Vp | Vg/Vp | |||
GLU0 | 0.52–0.65 | [41] | 1.71±0.96 | 90.13±1.50 | 1.9±1.1 | 0.27±3.08 | 90.72±1.49 | 0.2±3.4 |
ALB | 0.48–0.82 | [44] | 0.00±0.00 | 0.08±0.00 | 0.0±0.9 | 0.007±0.003 | 0.081±0.001 | 9.1±3.5 |
BUN | 0.27±0.10 | 8.02±0.13 | 3.4±1.2 | 0.32±0.28 | 8.02±0.13 | 4.0±3.4 | ||
GGT | 30 | [45] | 0.46±0.84 | 71.69±1.28 | 0.6±1.2 | 4.87±2.87 | 71.69±1.28 | 6.8±4.0 |
AST | 43 | [45] | 0.42±0.29 | 27.24±0.46 | 1.5±1.0 | 0.83±0.96 | 27.24±0.46 | 3.1±3.5 |
ALT | 40 | [45] | 1.55±0.94 | 85.15±1.44 | 1.8±1.1 | 7.54±3.07 | 85.15±1.46 | 8.9±3.5 |
HDLC | 0.68–0.86 | [41] | 1.04±1.08 | 70.52±1.47 | 1.5±1.5 | 4.19±3.88 | 70.52±1.47 | 5.9±5.5 |
LDLC | 0.37 | [42] | 26.23±9.22 | 673.72±12.39 | 3.9±1.4 | 99.13±29.70 | 673.80±12.39 | 15.7±4.4 |
Tchol | 0.26 | [43] | 19.19±9.89 | 781.03±14.19 | 2.5±1.3 | 113.77±33.40 | 781.06±14.20 | 14.6±4.2 |
TG | 0.39–0.53 | [41] | 16.17±16.48 | 1250.96±24.29 | 1.3±1.3 | 1.60±57.07 | 1250.98±24.28 | 0.1±4.6 |
Note. H2: previously reported heritability of the trait, Vg: estimated genetic variance, Vp: estimated phenotypic variance, Vg/Vp: percent of estimated genetic variance explained by SNPs for each trait.