Figure 3. Signaling through IL-17R is required for B cell migration.

B cells isolated from asthmatic (A) or healthy (B) subjects were treated with anti-IL-17RA or RC blocking antibodies or their isotype for 2 hrs prior to incubation with Th-17 cytokines for migration determination. Th-17 cytokines were used at 100 ng/ml. Data is presented as % migration of B cells relative to negative control (medium). (n = 7). Data is expressed as means ± SD. *P<0.05 is considered significant.