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. 2014 Nov 3;11(2):968–974. doi: 10.3892/mmr.2014.2838

Table II.

Antitumor effect of As4S4 in vivo.

Group Injection dosage (mg/kg) × ± standard deviation Tumor weight (g) Tumor inhibition (%)
Negative control 0 2.42±0.73 0
Positive control (cyclophosphamide) 20 0.59±0.16b 75.62
High As4S4 60 1.26±0.54a 47.93
Low As4S4 30 1.78±0.55 26.45

C57BL/6 mice were inoculated with Lewis lung carcinoma cells (106 cells/mouse), injected intraperitoneally with As4S4 for eight days and subsequently sacrificed. Data are expressed as the mean ± standard deviation.

a

P<0.01;

b

P<0.001 vs. negative control.

As4S4, arsenic sulfide.