Table I.
Group | Number | T3 (nmol/l) | T4 (nmol/l) | TSH (μIU/ml) |
---|---|---|---|---|
C | 12 | 0.83±0.03 | 49.81±1.08 | 1.02±0.14 |
Hypo | 11 | 0.60±0.03* | 18.19±1.72* | 19.78±3.01* |
DON | 11 | 0.57±0.02* | 18.58±0.91* | 19.55±3.29* |
T4 | 10 | 0.83±0.08 | 52.42±1.92 | 1.21±0.32 |
T4+DON | 11 | 0.77±0.07 | 52.71±2.04 | 1.07±0.15 |
Data are expressed as the mean ± SEM. C, control group; Hypo, hypothyroid group; DON, hypothyroid rats treated with 0.005% (w/v) DON; T4, hypothyroid rats treated with 6 μg T4/100 g body weight; T4+DON, hypothyroid rats treated with 6 μg T4/100 g BW beside adding 0.005% (w/v) DON to the drinking water.
P<0.01, vs. C.
T3, triiodothyronine; T4, thyroxine; DON, donepezil; THS, thyroid stimulating hormone; SEM, standard error of the mean; w/v, weight/volume.