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. 2014 Oct 30;11(2):775–782. doi: 10.3892/mmr.2014.2825

Table II.

syt-1 in different layers of each subfield in the hippocampus.

Subfield Stratum C Hypo DON T4 T4+DON
CA1 SO 5.06±0.15 3.49±0.13** 3.85±0.14** 4.09±0.20** 4.79±0.16
SR 4.75±0.19 3.19±0.14** 3.59±0.18** 3.70±0.29* 4.29±0.28
SLM 4.31±0.09 3.91±0.16 3.99±0.11 3.99±0.05 4.42±0.09
CA3 SO 5.01±0.18 4.55±0.17 4.71±0.08 4.87±0.10 4.98±0.14
SL 4.85±0.10 3.94±0.04** 3.95±0.05** 4.23±0.07** 4.71±0.08
SR 4.94±0.05 3.90±0.07** 4.05±0.05** 4.46±0.09** 4.81±0.06
DG ML 4.75±0.06 4.09±0.03** 4.18±0.09** 4.37±0.05** 4.61±0.05
PL 3.76±0.05 3.51±0.03 3.57±0.10 3.67±0.07 3.72±0.06

Data (mean ± SEM) are expressed as the average OD of syt-1 immunoreactivity (n=10–12). C, control group; Hypo, hypothyroid group; DON, hypothyroid rats treated with 0.005% (w/v) DON; T4, hypothyroid rats treated with 6 μg T4/100 g body weight; T4+DON, hypothyroid rats treated with 6 μg T4/100 g BW beside adding 0.005% (w/v) donepezil to the drinking water.

*

P<0.05,

**

P<0.01, vs. C.

Syt-1, synaptotagmin-1; T4, thyroxine; DON, donepezil; DG, dentate gyrus; SO, stratum oriens; SR, stratum radiatum; SLM, stratum lacunosum-moleculare; SL, stratum lucidum; ML, molecular layer; PL, polymorphic layer; SEM, standard error of the mean; OD, optical density; w/v, weight/volume.