Table 2.
Statistical analysis of the genotyping results from both C57/Bl6 Crb1rd8/rd8 lines 1 and 2 with either high (n = 11) or low (n = 11) number of autofluorescent fundus lesions
| SNP | Position in bp/Chr. 15 | P-value |
|---|---|---|
| rs13459176 | 3279130 | 1.01E−04 |
| CEL-15_8331158 | 8474279 | 1.03E−04 |
| CEL-15_9687257 | 9788004 | 6.22E−04 |
| rs13482431 | 11311464 | 6.22E−04 |
| rs3711814 | 13219494 | 6.22E−04 |
| CEL-15_15482356 | 15577251 | 9.27E−05 |
| rs13482455 | 16731203 | 9.27E−05 |
| rs13482469 | 20942406 | 9.27E−05 |
| rs13482477 | 22519205 | 9.27E−05 |
| rs13482485 | 25450871 | 9.27E−05 |
| rs13482504 | 30322280 | 2.91E−04 |
| rs13482509 | 32042169 | 2.91E−04 |
| rs6188239 | 34331233 | 2.91E−04 |
| rs3695416 | 38484397 | 2.91E−04 |
| CEL-15_43206205 | 43188178 | 2.91E−04 |
| rs13482543 | 43870893 | 2.91E−04 |
| rs13482558 | 47166660 | 2.91E−04 |
| rs13482571 | 49998375 | 2.91E−04 |
Listed are all informative SNPs that showed significant differences between the two groups based on a Pearson's χ2 test indicating the genomic region on chromosome 15 that is associated with the incidence of the AF-lesions phenotype.