(A) Serum total cholesterol (left), LDL cholesterol (middle) and leptin (right) of WT and Id2−/− under LFD or HFD. (B) Liver total cholesterol (left) and triglyceride (right) of WT and Id2−/− under LFD or HFD. (C) Representative Oil-red-O and Hematoxylin-Eosin stained liver section from WT and Id2−/− male mice liver fed with LFD or HFD. Scale bar, 100 μm. Oil-red-O quantification values, mean ± S.E.M., on the right. Two factor-ANOVAs were performed followed by Tukey’s post-hoc tests, *p<0.05, **p<0.01, ***p<0.001.