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Proposed mechanism of folding and insertion of the OmpA β-barrel domain into lipid bilayers in vitro. (a) Depicts an unfolded, membrane-bound state, (b) depicts a partially folded and inserted state, and (c) depicts the native state. Coloured circles indicate the location of tryptophan residues in the OmpA structure. Reproduced from [238] with permission from Elsevier, © 2011.
