Table 1.

Plasma lipid concentrations (mg/dL) (Mean ± SEM)

	TC	FC	CE	TG
L1-KO	120 ± 3^b	32 ± 1^ab	147 ± 4^b	69 ± 5^a
L1^IntOnly	141 ± 7^a	36 ± 2^a	176 ± 10^a	65 ± 4^a
L1^IntOnly&Ezet	113 ± 9^b	29 ± 2^b	140 ± 12^b	68 ± 12^a
DKO	306 ± 15^b	87 ± 6^b	365 ± 20^b	78 ± 4^b
DKO/L1^IntOnly	478 ± 5^a	191 ± 15^a	479 ± 33^a	119 ± 15^a
DKO/L1^IntOnly&Ezet	319 ± 15^b	83 ± 6^b	395 ± 27^b	99 ± 10^ab

Mice were fasted for 4 h during the daytime cycle prior to collection of blood samples for analyses of plasma concentrations of total cholesterol (TC), free cholesterol (FC), and triglyceride (TG). The amount of cholesterol ester was calculated by subtracting free cholesterol from total cholesterol and multiplying by 1.67 to convert to cholesterol ester mass. For each parameter, values among single L1-KO background groups [L1-KO (n = 11), L1^IntOnly (n = 8), and L1^IntOnly&Ezet (n = 7)] or among DKO background groups [DKO (n = 10), DKO/L1^IntOnly (n = 8), and DKO/L1^IntOnly&Ezet (n = 7)] not sharing a common superscript letter are significantly different (P < 0.05). Ezet, ezetimibe