Table 2.
Unadjusted and adjusted estimates (95% CI) for the association between natural log-transformed maternal urinary arsenic concentration and natural log-transformed cord blood leptin concentration (n=149*).
| Predictor | iAs | MMA | DMA | Total As |
|---|---|---|---|---|
| Ln[Arsenic species (μg/L)]1 | 0.02 (−0.12, 0.17) | 0.01 (−0.12, 0.14) | 0.04 (−0.08, 0.16) | 0.04 (−0.09, 0.16) |
| Ln[Arsenic species (μg/L)]2 | 0.09 (−0.05, 0.23) | 0.12 (−0.01, 0.25) | 0.14 (0.02, 0.26) | 0.14 (0.01, 0.27) |
| Creatinine (mg/dL) | 0.00 (−0.01,0.00) | 0.00 (−0.01, 0.00) | 0.00 (−0.01, 0.00) | 0.00 (−0.01, 0.00) |
| Infant birth weight %3 | 1.05 (0.64, 1.47) | 1.08 (0.66, 1.50) | 1.10 (0.68, 1.51) | 1.09 (0.68, 1.51) |
| Infant is Male | −0.38 (−0.60, −0.16) | −0.37 (−0.59, −0.15) | −0.37 (−0.58, −0.24) | −0.37 (−0.58, −0.15) |
| Maternal weight gain (lbs) | 0.00 (0.00, 0.01) | 0.01 (0.00, 0.01) | 0.00 (0.00, 0.01) | 0.01 (0.00, 0.01) |
| Maternal Education Level | ||||
| any high school | Reference | Reference | Reference | Reference |
| any college | −0.15 (−0.56, 0.26) | −0.17 (−0.58, 0.24) | −0.17 (−0.58, 0.24) | −0.17 (−0.58, 0.24) |
| college graduate | −0.10 (−0.50, 0.29) | −0.13 (−0.53, 0.26) | −0.14 (−0.53, 0.25) | −0.14 (−0.53, 0.25) |
| any postgraduate | −0.29 (−0.73, 0.15) | −0.31 (−0.59, 0.36) | −0.34 (−0.58, 0.35) | −0.34 (−0.77, 0.35) |
1
Models unadjusted.
2
Models adjusted for all other variables in the table.
3
Infant birth weight for gestational age percentile from Fenton & Kim, 2013 (n=2 missing).
Urinary arsenic metabolites were measured via HPLC. Total urinary arsenic (Total As) is the sum of inorganic arsenic (iAs), monomethylarsonic acid (MMA), and dimethylarsinic acid (DMA); arsenobetaine was not included in this total.
*
Includes white mother-infant pairs only