Table 4.
Vaginal interleukin-1β levels in vaginal secretions of women with VVS symptoms and control subjects in relation to the dominant bacterial genus or species present.
| Bacteria | Median IL-1β in pg/ml (range) a |
||
|---|---|---|---|
| Controls | VVS | Combined | |
| L. crispatus | <3.9 (<3.9-211) | 4.5 (<3.9-91) | <3.9 (<3.9-211) |
| L .iners | 18.2 (7.5-258) | 53.5 (<3.9-107) | 18.2 (<3.9-258) |
| Gardnerella | 100 (<3.9-200) | 134 (29-534) | 118 (<3.9-534)b |
a
Vaginal secretions were analyzed for concentrations of IL-1β by a commercial ELISA kit. The number of women in the control and VVS groups dominant for L. crispatus was 8 and 8, for L. iners 2 and 10 and for Gardnerella 5 and 3, respectively.
b
p = 0.0026 Gardnerella vs. L. crispatus and 0.0425 Gardnerella vs. L. iners.