Table I.
Microparticle levels and laboratory markers of haemolysis, coagulation and inflammation.
| Mean Values (SD) | Normal Reference Range | P-value of least square means | Correlation, r (p-value) | |||||
|---|---|---|---|---|---|---|---|---|
| + ONFH | − ONFH | Control | + ONFH vs − ONFH | + ONFH vs Control | − ONFH vs Control | +ONFH | ||
| Microparticles 1010 particles/ml plasma | 4.55 (2.26) | 1.99 (1.08) | 1.85 (1.09) | N/A | 0.003 | 0.002 | ns | -- |
| WBC × 109/l | 10.54 (4.8) | 9.53 (5.29) | 7.25 (1.52) | 5–10 | ns | ns | ns | +0.25 (ns) |
| Hb g/l | 96 (13) | 94 (18) | 134 (13) | 135–173 | ns | <0.001 | <0.001 | +0.03 (ns) |
| Plt × 109/l | 340 (167) | 302 (100) | 260 (42) | 150–400 | ns | ns | ns | 0.00 (ns) |
| ARC 109/l | 258 (140) | 278 (140) | 61.4 (20) | 36–159 | ns | 0.0002 | 0.0006 | +0.80 (0.006) |
| Tbili umol/L | 36.1 (22.2) | 45 (28.2) | 10.3 (2.1) | 1.7–25.7 | ns | 0.03 | 0.003 | +0.43 (ns) |
| LDH u/l | 712 (159) | 862 (503) | 439 (52) | 313–618 | ns | ns | 0.01 | +0.10 (ns) |
| hsCRP mg/l | 9.26 (8.71) | 3.26 (2.83) | 2.45 (3.31) | 0.1–3.0 | ns | 0.002 | ns | +0.03 (ns) |
| VWF:Ag % | 143.4 (73.7) | 121.3 (46.0) | 83.6 (28.2) | 51–185 | ns | 0.04 | ns | −0.42 (ns) |
| Tissue Factor pg/ml | 169.7 (155.2) | 250.1 (150.7) | 161.3 (125.1) | N/A | ns | ns | ns | −0.28 (ns) |
| D-Dimer ng/ml | 1254.8 (926.1) | 1579.4 (1431.0) | 168.2 (131.1) | <400 | ns | 0.05 | 0.01 | +0.64 (0.05) |
ONFH, osteonecrosis of the femoral head; WBC, white blood cell count; Hb, haemoglobin; Plt, platelet count; ARC, absolute reticulocyte count; Tbili, total bilirubin; LDH, lactate dehydrogenase; hsCRP, highly-sensitive C-reactive protein; VWF:Ag, von Willebrand factor antigen; SD, standard deviation; N/A, not ns, not significant.