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. Author manuscript; available in PMC: 2015 Dec 30.
Published in final edited form as: Stat Med. 2014 Jul 14;33(30):5239–5248. doi: 10.1002/sim.6266

Table 1.

Comparison of treatment allocation randomness

MTI Probability of deterministic assignment Correct guess probability
PBD BSD BUD MP PBD BSD BUD MP
1 0.500 0.500 0.500 0.500 0.750 0.750 0.750 0.750
2 0.333 0.250 0.167 0.166 0.708 0.625 0.667 0.666
3 0.250 0.167 0.059 0.073 0.683 0.583 0.632 0.624
4 0.200 0.125 0.021 0.038 0.665 0.562 0.613 0.598
5 0.167 0.100 0.008 0.022 0.653 0.550 0.600 0.582
6 0.143 0.083 0.003 0.014 0.643 0.542 0.590 0.569
7 0.125 0.071 0.001 0.009 0.633 0.536 0.583 0.560
8 0.111 0.063 0.000 0.007 0.625 0.531 0.577 0.553

MTI: Maximal Tolerated Imbalance.

PBD: Permuted block design. Data obtained based on formulas in [4] and Hypergeometric distribution.

BSD: Big Stick Design. Data obtained based on formulas in [30,31].

BUD: Block Urn Design. Data obtained from [29].

MP: Maximal Procedure. Data obtained based on computer simulation with sample size = 300, using algorithm provided by Salama at el. in [32]. Ten thousand simulation runs are performed for each scenario.