Figure 2. In situ hybridization for Crisp1.
There is no Crisp1 expression in representative anagen follicles from an adult AA affected C3H/HeJ mouse (A) in contrast to the blue signal in the medulla of an FVB/NTac albino mouse (B). Hair shafts were clipped from 2 adult females and 2 adult males. Note the dystrophic hair shaft in the bulb of the C3H/HeJ mouse hair follicle (A, arrow). Crisp1 expression was not detectable in normal hair shafts from 5 day old C3H/HeJ mice (C) in contrast to control 5 day old FVB/NTac mice (D). Size bar = 40μm.