Table 3.
Levels (median (IQR)) of MetS criteria by MetS status at week 96.
MetS at ART initiation (N=450) | Follow-up at week 96 (N=378) | ||
---|---|---|---|
MetS at ART initiation and week 96 (N=239) | MetS at ART initiation and no MetS at week 96 (N=139) | ||
Waist circumference (cm) | |||
ART initiation | 101 (91, 109) | 104 (96, 112)* | 93 (85, 104)* |
Week 96 | 101 (93, 110) | 106 (98, 114)* | 93 (86, 100)* |
Change at week 96 | 1.5 (−3, 6) | 2 (−3, 8) † | 0 (−5, 4) † |
Systolic blood pressure (mm Hg) | |||
ART initiation | 130 (120, 139) | 131 (120, 141) † | 128 (120, 136) † |
Week 96 | 127 (118, 138) | 130 (120, 140)* | 122 (113, 130)* |
Change at week 96 | −1 (−11, 7) | −1 (−10, 8) † | −3 (−12, 4) † |
Diastolic blood pressure (mm Hg) | |||
ART initiation | 82 (75, 90) | 83 (76, 90) † | 81 (74, 88) † |
Week 96 | 80 (74, 86) | 80 (75, 87)‡ | 78 (72, 81) ‡ |
Change at week 96 | −3 (−9, 4) | −2 (−9, 5) ‡ | −5 (−9, 2) ‡ |
HDL cholesterol (mg/dl) | |||
ART initiation | 32 (27, 37) | 32 (27, 37) † | 34 (29, 38) † |
Week 96 | 39 (33, 48) | 37 (31, 44)* | 45 (40, 54)* |
Change at week 96 | 8 (2, 13) | 6 (2, 11)* | 12 (5, 18)* |
Fasting glucose (mg/dl) | |||
ART initiation | 92 (83, 104) | 93 (84, 107) † | 89 (80, 103) † |
Week 96 | 97 (88, 108) | 102 (92, 114)* | 90 (83, 95)* |
Change at week 96 | 5 (−5, 14) | 6 (−3, 17) † | 1.5 (−8, 10) † |
Fasting triglycerides (mg/dl) | |||
ART initiation | 180 (126, 235) | 184 (131, 237) † | 175 (125, 227) † |
Week 96 | 199 (135, 285) | 223 (171, 301)* | 135 (98, 201)* |
Change at week 96 | 19 (−39, 93) | 47 (−12, 131)* | −21 (−89 30)* |
Comparison between patients with MetS at ART initiation and week 96 and patients with MetS at ART initiation and no MetS at week 96:
p-value<0.0001;
p<0.05;
p>0.05